Rare Fractures Linked To Drugs For Weak Bones : NPR

The study found 716 atypical fractures among more than 200,000 Ontario women over 68. The researchers calculate the risk at one or two atypical fractures for every 1,000 women who took bisphosphonate drugs for more than five years.

Enlarge Courtesy of Dr. Jennifer Schneider

An X-ray of Schneider's right femur (thighbone), which broke suddenly as she was standing on a New York subway train.

Courtesy of Dr. Jennifer Schneider

An X-ray of Schneider's right femur (thighbone), which broke suddenly as she was standing on a New York subway train.

That's fairly rare, and considerably less than the risk of another potential side effect from these drugs, a condition called osteonecrosis of the jaw — the death of part of the jawbone, following a major dental procedure. Still, since tens of millions of women are taking bisphosphonates, the Ontario study suggests thousands of them may suffer devastating atypical fractures every year.

But here's the dilemma: Many women really need these drugs, because they really do work to prevent ordinary hip fractures caused by osteoporosis.

via npr.org

Click on the "Via" link to read the full article.

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