Sunday, October 17, 2021

#Covid19Vaccines, what did clinical trials so far evaluate? Ability to prevent infection, transmission to others? No, just "prevention of severe disease" unfortunately, but future trials are looking to assess those and other "endpoints." Standardizing Clinical Endpoints for COVID-19 Vaccine Efficacy Trials:"According to the authors, while prevention of severe COVID-19 is an important and expected benefit of a vaccine, the broader encompassing endpoint of symptomatic COVID-19 disease is needed because severe cases are a relatively small proportion of cases overall and vary widely based on other factors. The statistical power to show adequate efficacy against severe cases may be lower than what is needed in non-severe cases." https://www.infectiousdiseaseadvisor.com/home/topics/covid19/consistent-coronavirus-vaccine-trial-endpoints-help-facilitate-meta-analyses/


#NurseUp #Covid19Vaccines

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