The anticoagulant Pradaxa (dabigatran) is associated with a small increase in the risk of heart attack, a new review finds.
Researchers from the Cleveland Clinic in Ohio looked at seven trials involving Pradaxa that included more than 30,000 patients. This process, called a meta-analysis, uses data from published clinical trials to tease out a pattern that might not show up in a single study.
The researchers found Pradaxa was associated with an increased risk of heart attack or acute coronary syndrome (heart attack or angina), compared with two other commonly used blood thinners, warfarin (Coumadin, Jantoven) and enoxaparin (Lovenox).
Among those taking Pradaxa, 1.19 percent had a heart attack or suffered from acute coronary syndrome compared with 0.79 percent of those taking either of the other drugs, they noted.
Andrew Lopez, RN
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