Nursefriendly.com: unsafe prescription drugs

Showing posts with label unsafe prescription drugs. Show all posts

Thursday, April 21, 2011

Popular birth control pills may boost clot risk (Yasmin, Yaz-Drospirenone )- Health - CBC News

Two of the most popular birth control pills available in Canada — Yasmin and Yaz — carry a higher risk of serious blood clots than some other oral contraceptives, two new studies say.

The studies — both published Thursday in the online edition of the British Medical Journal — show that pills containing a new type of progestogen hormone called drospirenone carry up to triple the risk of serious blood clots (known as venous thromboembolisms) over an older generation of pills containing a hormone called levonorgestrel.

Drospirenone is the key ingredient in Yasmin and Yaz, which are manufactured by Bayer and widely prescribed in Canada.

Drospirenone-based pills like Yasmin and Yaz had worldwide sales of $2 billion US in 2009, reports indicate.

via cbc.ca

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Monday, February 28, 2011

Rare Fractures Linked To Drugs For Weak Bones : NPR

The study found 716 atypical fractures among more than 200,000 Ontario women over 68. The researchers calculate the risk at one or two atypical fractures for every 1,000 women who took bisphosphonate drugs for more than five years.

Enlarge Courtesy of Dr. Jennifer Schneider
An X-ray of Schneider's right femur (thighbone), which broke suddenly as she was standing on a New York subway train.

Courtesy of Dr. Jennifer Schneider
An X-ray of Schneider's right femur (thighbone), which broke suddenly as she was standing on a New York subway train.

That's fairly rare, and considerably less than the risk of another potential side effect from these drugs, a condition called osteonecrosis of the jaw — the death of part of the jawbone, following a major dental procedure. Still, since tens of millions of women are taking bisphosphonates, the Ontario study suggests thousands of them may suffer devastating atypical fractures every year.

But here's the dilemma: Many women really need these drugs, because they really do work to prevent ordinary hip fractures caused by osteoporosis.

via npr.org

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Tuesday, February 22, 2011

Prescription Medications Take on Leading Role in Illegal Drug Trade - Nursing Link

Brian Freskos | Star-News, Wilmington, N.C.

February 22, 2011

Feb. 17—When Lt. J.A. LeBlanc arrived at the New Hanover County Vice and Narcotics Unit in 2001, one detective could handle the volume of prescription drug cases. Now, he said, all 16 detectives investigate them.

Street drugs such as cocaine and heroin have long been the targets of authorities seeking to root out illicit substances. But in recent years, growing prescription drug abuse has shifted law enforcement’s focus to stemming the flow of dangerous medications onto the black market.

Abuse of prescription medications, particularly narcotic pain relievers such as hydrocodone and oxycodone, is rising precipitously, leading White House drug czar Gil Kerlikowske last June to call it the “nation’s fastest-growing drug problem.” Between 1998 and 2008, treatment admissions for prescription pill addicts posted a 400 percent increase, according to the federal Substance Abuse and Mental Health Services Administration.

Southeastern North Carolina has not escaped what many law enforcement officials call an epidemic. Between 2004 and 2010, the New Hanover County Vice and Narcotics Unit seized nearly 15,100 pills — 3,749 of them in 2010 alone, the largest county pill haul in four years.

via nursinglink.monster.com

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Monday, January 31, 2011

Institute For Safe Medication Practices

Newsletters Professional Development

Consulting Services Self Assessments

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NEW Standard Concentrations of Neonatal Drug Infusions

FDA and ISMP List of Drug Names with Tall Man Letters

Guidelines for Standard Order Sets

Tool to assess risk in community pharmacy

Quarterly Action Agenda (Free CE)

High-Alert Medication List

Updated Confused Drug Name List

Community Pharmacy Medication Safety Tools and Resources

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List of Products with Drug Name Suffixes

Error-Prone Abbreviation List

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Monday, January 3, 2011

New Drug Approvals Slipped in 2010 - WSJ.com

The Food and Drug Administration approved about 21 drugs in 2010, a relatively modest figure that shows the pharmaceutical industry hasn't yet escaped its drought in recent years.

A few potential blockbusters won approval during the year, but some of the most highly anticipated new products got delayed into next year or beyond. That partly reflects a tougher environment at the FDA, with regulators stepping up their scrutiny of safety issues in drugs for obesity, diabetes and other conditions.

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According to monthly drug-approval reports on the FDA's website, 21 new drugs were approved in 2010, down from 25 in 2009 and 24 in 2008, but higher from a recent low of 18 in 2007.

The final approval figures, as well as the number of applications received by the agency in 2010, won't be available until next month. The approval figures don't include dozens of approvals granted for new formulations or new uses of existing drugs.

Although the 2010 figures are a bit lower than previous years, FDA spokeswoman Sandy Walsh said there's "no systemic change in how the FDA is approaching drug approvals."

The figures include several major biologic drugs, which are created from living cells and represent a growing portion of the pharmaceutical market. Amgen Inc. won approval for Prolia, a drug that is injected twice yearly to treat osteoporosis in postmenopausal women. Roche Holding AG's biotechnology unit, Genentech, won approval for Actemra, a drug that's administered intravenously to treat rheumatoid arthritis.

via online.wsj.com

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Sunday, January 2, 2011

Drug recalls surge to more than 1,700 in 2009 - Aug. 16, 2010

Recalls of prescription and over the counter drugs are surging, raising questions about the quality of drug manufacturing in the United States.
The Food and Drug Administration reported more than 1,742 recalls last year, skyrocketing from 426 in 2008, according to the Gold Sheet, a trade publication on drug quality that analyzes FDA data.

One company, drug repackager Advantage Dose, accounted for more than 1,000 of those recalls. Even excluding Advantage Dose, which has shut down, recalls jumped 50% last year.

"We've seen a trend where the last four years are among the top five for the most number of drug recalls since we began tallying recalls in 1988," said Bowman Cox, managing editor of the Gold Sheet. "That's a meaningful development."

The fast pace of drug recalls seems to be continuing in 2010. Drug recalls totaled 296 from January through June of this year, said Cox. "If we continue at this same rate, we could get 600 or more recalls by the end of the year," he said. "That's still a very high rate of recalls."

via money.cnn.com

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Thursday, April 21, 2011

Popular birth control pills may boost clot risk (Yasmin, Yaz-Drospirenone )- Health - CBC News

Monday, February 28, 2011

Rare Fractures Linked To Drugs For Weak Bones : NPR

Tuesday, February 22, 2011

Prescription Medications Take on Leading Role in Illegal Drug Trade - Nursing Link

Monday, January 31, 2011

Institute For Safe Medication Practices

Monday, January 3, 2011

New Drug Approvals Slipped in 2010 - WSJ.com

Sunday, January 2, 2011

Drug recalls surge to more than 1,700 in 2009 - Aug. 16, 2010

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